Content Determination of Clobetasol Propionate in Temeifu Pigmentum by UV Spectrophotometry
- VernacularTitle:紫外分光光度法测定特美肤涂剂中丙酸氯倍他索的含量
- Author:
Peiying JI
;
Zengshou WANG
;
Guanghui ZHU
- Publication Type:Journal Article
- Keywords:
UV spectrophotometry;
Temeifu pigmentum;
Clobetasol propionate;
Content
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for quick content determination of clobetasol propionate in temeifu pigmentum.METHODS:UV spectrophotometry was used,and the determination was performed at the wavelength of 240nm.RES-ULTS:The detectable concentration of clobetasol propionate have a good linear relationship with its absorbability in the range of 12～18?g/ml.The inter-day and intra-day average recoveries were 99.87%(RSD=1.21%) and 99.79%(RSD=1.01%),respectively.CONCLUSIONS:The present method is rapid and accurate,which can be widely used in small hospitals not equipped with high performance liquid chromatography.
