Combined therapy on chronic nasal-sinusitis
- VernacularTitle:综合治疗在慢性鼻及鼻窦炎黏膜炎症恢复中的作用
- Author:
Jin YE
;
Yuan LI
- Publication Type:Journal Article
- Keywords:
Sinusitis;
Nasal Polyps;
Endoscopy;
Surgical Procedures,Operative;
Combined Modality Therapy
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the efficacy of combined therapy on chronic rhinosinusitis(CRS). METHODS Thirty cases with CRS in stage Ⅱ-2 were treated by FESS. At 1,3,6-month after operation,endoscopy and nasal mucosa biopsy were performed and the clinic symptoms were reassessed. RESULTS Although fine mucosal epithelization was found in all cases at 6 month after operation,mild edema of mucosa and muciform secretion still existed in 10 cases. Mucociliary transport rate (MTR) was 3.63?1.74 mm/min before operation,and was 6.27?1.31 mm/min at 6-month after operation. Compared with that before operation,the MTR was significantly improved whereas it had not rehabilitated to normal status. The decrease of inflammatory cells and alleviation of submucosal edema were observed in the mucosa of maxillary sinus. Nevertheless,the number of goblet cells and submucosa glands did not improve significantly. The ultrastructure of the mucosa was not recovered completely at 6 month after operation. CONCLUSION With combined therapy on CRS for 6 months, clinical cure can be achieved,but mucosal inflammatory reaction is still existed.
