Value of serum NT-proBNP in the clinical evaluation of heart failure
- VernacularTitle:血清N末端B型钠尿肽原对心力衰竭患者的临床评估
- Author:
Qing WANG
;
Feng LENG
;
Zhi LI
;
Yiwen CUI
- Publication Type:Journal Article
- Keywords:
NT-proBNP;
Heart failure;
Cardiac function classification
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationships between the concentration of serum NT-proBNP,New York Heart Association(NYHA) classification,left ventricular ejection fraction((LVEF),)and the value of serum NT-proBNP in the evaluation of cardiac function and the diagnosis of chronic heart failure.Methods One hundred and two subjects were selected,including 30 healthy controls and 72 patients with heart failure.The concentration of serum NT-proBNP was determined by an automated electrochemiluminescence immunoassayan Roche Elecsys 2010.LVEF was measured by the modified Simpson′s equation with echocardiography.The diagnosis of clinical physician was considered to be the golden standard for heart failure.Results The relationships between the concentration of serum NT-proBNP and NYHA,serum NT-proBNP levels(287.7 pg/ml) was significantly higher in heart failure patients(287.7 pg/ml) than that in healthy controls 287.7 pg/ml vs (46.1 pg/ml),P
