The relationship between angiogenesis of cholangiocarcinoma and clinical pathology and prognosis
- VernacularTitle:胆管癌微血管生成及其病理学特征与预后的关系
- Author:
Bo SHEN
;
Xiujun CM
;
Hong YU
;
Xiao LIANG
;
Jida CHEN
;
Lizhong LIN
;
Jin YANG
- Publication Type:Journal Article
- Keywords:
Bile duct neoplasms;
Neovascularization, pathologic;
Endothelial growth factors;
Prognosis
- From:
Chinese Journal of General Surgery
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between angiogenesis and pathology and prognosis of cholangiocarcinoma. Methods Immunohistochemistry was used to determine micro-vessel density (MVD) and the expression of vascular endothelial growth factor(VEGF) and its receptor Flk-1/KDR in 50 cholangiocarcinoma cases. Results were compared with pathological and follow-up parameters. Results MVD in cholangiocarcinoma tissues and para-tumor tissues (34.04 ? 11.08, 32.80 ?9.28) were higher than normal bile duct tissues ( 11. 67 ? 4. 64) ( P
