Long-term effect of flow-restricted portal vein arterialization on rat's liver structure and function
- VernacularTitle:限制流量的门静脉动脉化对大鼠肝脏功能和结构的远期影响
- Author:
Wengang LI
;
Bin LI
;
Lijie GAO
;
Aiqun ZHANG
;
Tao WAN
;
Yongliang CHEN
;
Zhiqiang HUANG
- Publication Type:Journal Article
- Keywords:
Portal vein;
Arteries;
Models, animal
- From:
Chinese Journal of General Surgery
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore long-term effects of flow-restricted portal vein arterialization on hepatic function and structure in a rat model. Methods SD rats were divided into three groups to undergo respectively total portal vein arterialization ( PVA) , arterial inflow restricted portal vein arterialization (RPVA) ,and sham operation (SO). Postoperative portal blood flow and cross section after one month and six months, portal vein pressure, liver function and structure after six months were observed. Results The cross section and blood flow of the portal vein in PVA group consistently increased, serum ALT level was elevated after six months(F=7. 72,P
