Compatible Stability of Gatifloxacin for Injection with Metronidazole Disodium Phosphate
- VernacularTitle:注射用加替沙星与甲硝唑磷酸二钠的配伍稳定性考察
- Author:
Jizhang YANG
;
Ruiqin LIU
;
Shumin YANG
- Publication Type:Journal Article
- Keywords:
Ultraviolet spectrophotometry;
Gatifloxacin;
Metronidazole disodium phosphate;
Compatibility;
Stability
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatible stability of gatifloxacin for injection with metronidazole disodium phos-phate in sodium chloride injection.METHODS:The contents of2constituents of the mixed solution stored at25℃within8hours was determined by dual ultraviolet wavelength spectrophotometry,and the appearance,pH value of the mixture were compared with those before.RESULTS:There was no significant change in the content of gatifloxacin after mixing,while the content of metronidazole disodium phosphate has a slight reduction,no significant changes were noted otherwise.CONCLUSI_ ON:Gatifloxacin for injection is compatible with metronidazole disodium phosphate in sodium chloride injection if at25℃within4hours'mixing.
