Role of serotonin in the gastrointestinal function and pathogenesis of the irritable bowel syndrome
- VernacularTitle:5-羟色胺在肠易激综合征发病机制中的作用
- Author:
Yajie WANG
;
Xiaoxin ZHU
- Publication Type:Journal Article
- Keywords:
Serotonin;
Colonic diseases, functional
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[A Review] The irritable bowel syndrome (IBS) is a chronic functional bowel disorder,and its pathogenesis remains unclear. Serotonin is thought to be an important brain-gut axis neurotransmitter,which plays an important role in the gastrointestinal motility,sensation and secretion. Serotonin is closely associatied with IBS and regarded as one of the therapeutic targets. This article reviews the related investigations in the recent years.