0.05% desonide cream for the treatment of patients with eczema: a ramdomized, double-blind, multicenter study
- VernacularTitle:0.05%地奈德乳膏治疗湿疹的多中心随机双盲、对照研究
- Author:
Jianfang SUN
;
Zhizhong ZHENG
;
Jun GU
;
Xuesi ZENG
;
Wenwen FU
;
Xinling BI
- Publication Type:Journal Article
- Keywords:
Eczema;
Randomized controlled trials;
Desonide
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of 0.05% desonide cream in the treatment of patients with eczema. Methods A randomized, double-blind, multicenter, vehicle-controlled study was conducted. The patients of the study and control groups applied 0.05% desonide cream and vehicle respectively, twice daily for 3 consecutive weeks. The efficacy was determined by measuring the total scores of erythema, erosion, infiltration, papule, exudation/crust, pruritus and the extent of lesions. Results At the end of the 3 weeks study, the total clinical effective rate was 80.8% in the study group,compared to 41.1% in the control group, with a significant difference between the two groups (P
