The expressions of hormone receptors and oncogene in the patients with breast cancer and their clinical significance
- VernacularTitle:乳腺癌激素受体和癌基因的表达及临床意义
- Author:
Meirong LI
;
Songqing FAN
;
Liqun ZHANG
;
Yi JIANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Receptors,estrogen;
Receptors,progesterone;
Carcinoembryonic antigen;
Genes,erbB-2
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationships between the expressions of estrogen receptor(ER),progesterone receptor(PR),carcinoembryonic antigen(CEA),c-erbB-2,and clinicopathologic parameters of the breast cancer and to evaluate their value in predicting the prognosis of breast cancer.Methods The databank of clinical data and expressions of ER,PR,CEA and c-erbB-2 proteins in 791 cases of breast cancer were established and the results were analyzed by using chi-square test,Kaplan-Meier(SPSS10.0).Results The positive expression rates of ER,PR,CEA and c-erbB-2 were 64.6%,66.5%,45.5% and 66.2% in the 791 breast cancers,respectively.The positive rate of ER expression in the infiltrating lobular carcinomas was significantly higher than that of the infitrating ductal carcinomas of breast(P
