The Expression and Clinical Significance of MMP-9 and VEGF in Breast Cancer
- VernacularTitle:MMP-9和VEGF在乳腺癌的表达及临床意义
- Author:
Hualin ZHANG
;
Aiguo WU
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Immunohistochemistry;
Metalloproteinase-9 (MMP-9);
Vascular endothelial growth factor (VEGF)
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of Matrix metalloprotein-9 (MMP-9) and Vascular Endothelial Growth Factor (VEGF) in breast cancer. HZ Methods SP immunohistochemistry was used to determine the expression of MMP-9 and VEGF in 96 breast cancer tissues. Results The positive rate of MMP-9 in breast cancer was 65.6 %,while the positive rate of VEGF was 71.9%. Both MMP-9 and VEGF postivity was correlated with pathological stage and lymphatic metastasis.There was a positive correlation between the expression of MMP-9 and that of VEGF in breast cancer tissues( P
