Effect of Serum High Sensitive C-reactive Protein Levels in Patients with Unstable Angina and Early Intervention with Atovastatin
- VernacularTitle:阿托伐他汀早期干预对不稳定型心绞痛患者hs-CRP水平的影响
- Author:
Youzhuang HU
;
Bin YANG
;
Dehui FENG
- Publication Type:Journal Article
- Keywords:
Unstable angina;
Atovastatin;
High sensitive C-reactive protein;
Inflammation
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relations between UA and serum hs-CRP, the effects of early intervention with atovastatin on serum hs-CRP in patients with UA and its clinical significance in the early management of UA. Methods T 60 patients with UA (UA group),53 patients with stable angina (SA group) and 50 healthy controls (control group) were enrolled to the study. The serum hs-CRP levels were measured by particle enhanced immunoturbidimetric assay. UA group were randomly assigned to the atovastatin group and the routine group for a 4-week treatment immediately after admission. Selected coronary artery angiography was performed in 78 patients and 29 healthy controls with Judkin's technique. Results Baseline of hs-CRP in patients with UA was significantly higher than those in SA group and control group ( P