Distribution of Connexin 26 and 32 in the Cochlea of Guinea Pig
- VernacularTitle:连接蛋白26和32在豚鼠内耳的分布
- Author:
Peng WANG
;
Shusheng GONG
;
Peng SONG
- Publication Type:Journal Article
- Keywords:
Connexin;
Guinea pig;
Cochlea
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the distribution of the gap conjunction and connexin(Cx)26 and 32 in inner ear of guinea pig. Methods We investigated expression and distribution of gap conjunction and Cx 26 and Cx 32 in cochlea of guinea by immunohistochemistry, RT-PCR and electron microscopy. Results T The gap conjunction was easily seen between hair cells and supporting cells in cochlea of guinea pigs. Cx26 was widely distributed in the stria vascularis, the spiral ligament and between the supporting cells, and Cx32 appeared mainly among supporting cells, in the stria vascularris. Conclusion There exist lots of gap conjunctions in inner ear of guinea pig. Two kinds of connexins can be seen in guinea pig's cochlea, and the Cx 26 plays more important role than other Cx.
