A study on the influence of laparoscopic resection of colorectal cancer on micrometasis of tumor cells
- VernacularTitle:腹腔镜结直肠癌根治术对肿瘤细胞微转移影响的研究
- Author:
Kun ZHOU
;
Haiyan GE
- Publication Type:Journal Article
- Keywords:
Colorectal Neoplasms/surg;
Surgery laparoscopy;
Neoplasms Metastasis
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of laparoscopic resection of colorectal cancer on (postoperative) micrometastasis of tumor cells.Methods Using cytokeratin,CK-20 mRNA as target gene,the RT-PCR method was used to examine the pre-and post-operative changes in the number of tumor cells in the peripheral blood of 48 cases of colorectal cancer.Results After operation,the number of tumor cells in(peripheral) blood was significantly higher in the laparoscopic surgery group as compared to that of traditional(laparotomy) operation group(P0.05),but was significantly related to positive rate of proliferating cell nuclear antigen(PCNA)(P
