Preparation and Quality Control of Moxifloxacin Hydrochloride Gel
- VernacularTitle:盐酸莫西沙星凝胶的制备及质量控制
- Author:
Jinwei LI
- Publication Type:Journal Article
- Keywords:
Moxifloxacin hydrochloride;
Gel;
Preparation;
Quality control
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare moxifloxacin hydrochloride gel and to establish a quality control method for the gel.METHODS:The gel was prepared with carbopol934as base,the content of moxifolxacin hydrochloride was determined by HPLC and the stability of which was investigated.RESULTS:The linear range of moxifloxacin hydrochloride was0.4?g～3?g(r=0.9999),the average recovery was98.41%(RSD=1.42%,n=6).CONCLUSION:The gel is reasonable in perfor?mulation,satisfactory in stability,and accurate and reliable in quality control.
