Observation on Therapeutic Effects of Chemotherapy Involving Oxaliplatin in Treatment of Advanced Na-sopharyngeal Carcinoma
- VernacularTitle:含奥沙利铂的化疗方案治疗晚期鼻咽癌疗效观察
- Author:
Weijian SHI
;
Qiaoyun ZHOU
;
Wendong JU
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal carcinoma;
Oxaliplatin;
Chemotherapy;
Therapeutic effects
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effects as well as adverse durgs reactions of chemotherapy involving oxaliplatin in treatment of advanced nasopharyngeal carcinoma(NPC).METHODS:28patients with advanced NPC underwent chemotherapy with5-Fu,tetrahydrofolic acid calcium,and oxaliplatin for21days as one cycle,the therapeutic effects were evaluated after two cycles.Meanwhile the retrospective comparative study was made between the chemotherapy and the regular chemotherapy with5-Fu,tetrahydrofolic acid calcium,and platinum.RESULTS:Similar effects were observed in both regimens.How?ever,there were great differences in incidence ofⅢandⅣgrade nausea and vomiting,as well as renal function indices(P
