Content Determination of Sophocarpidine in Fuyankang Concentrated Pill by HPLC
- VernacularTitle:高效液相色谱法测定妇炎康浓缩丸中苦参碱的含量
- Author:
Ying WANG
- Publication Type:Journal Article
- Keywords:
High performance liquid chromatography;
Fuyankang concentrated pill;
Sophocarpidine;
Content
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the content of sophocarpidine in Fuyankang concentrated pill by HPLC.METHO_ DS:The loading agent of chromatographic column was amino bonded silica,the mobile phase was acetonitrile-dehydrated al?cohol-3%phosphoric acid(80∶10∶10),and the detection wavelength was220nm.RESULTS:There was a good linear rela?tionship between sample size and peak area score of sophocarpidine in the range of0.4064?g~2.0320?g,the average recovery rate was99.2%(RSD=1.6%).CONCLUSION:The established method is more accurate than TLC,and it can be used for the quality control of Fuyankang concentrated pill.