The effects of lifestyle intervention associated with Metformin on the C reactive protein and interleukin-6 in the aged people with metabolic syndrome
- VernacularTitle:生活干预加二甲双胍对老年代谢综合征患者CRP和IL-6水平的影响
- Author:
Ji ZHANG
;
Huixia LIU
;
Manxiang DENG
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome;
C-reactive protein;
Interleukin-6;
Metformin
- From:
Journal of Chinese Physician
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Ojective To observe the effects of lifestyle intervention associated with Metformin on the blood biochemical index,C reactive protein(CRP) and interleukin-6(IL-6) in the aged people with metabolic syndrome(MS).Mtthods Fifty-nine old patients with MS were randomly divided into lifestyle intervention group(n=29) and lifestyle intervention associated with Metformin group(n=30).The index of body mass index(BMI) and blood pressure(BP),the levels of fasting blood sugar(FBS),triacylglycerol(TG),high density lipoprotein cholesterol(HDL-C),fasting insulin(FINS),serum C-reactive protein(CRP) and interleukin-6(IL-6) were detected before and after the treatment.Result The levels of systolic blood pressure(SBP),BMI,FBS,TG,CRP,IL-6 and the homeostasis assessment of insulin resistance(HOMA-IR) were significantly lower in the lifestyle intervention associated with Metformin group than those of the lifestyle intervention group(P
