Preparation and Quality Control of Disinfectant for Venepuncture in Children
- VernacularTitle:小儿静脉穿刺消毒液的制备及质量控制
- Author:
Peiye HUI
;
Meihe LIU
;
Wenhua WEI
;
Hong ZHAO
;
Aifen FU
;
Feng LIU
- Publication Type:Journal Article
- Keywords:
Racanisodamine;
Nicotinic acid;
Laurocapram;
Preparation;
Quality control
- From:
China Pharmacy
2005;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To prepare the disinfectant for venepuncture in children and to establish the quality control for this preparation. METHODS: Nicotinic acid and racanisodamine were taken as the chief components for the preparation of this disinfectant, 75% alcohol as the solvent. Nicotinic acid were determined by ultraviolet and visible spectrophotometry(UV-Vis); racanisodamine were determined by nonaqueous titrations. RESULTS: The average recoveries of racanisodamine and nicotinic acid were 99.96%(RSD=0.04%) and 100.04%(RSD=0.16%) respectively, which all were in the range of 98.87%～100.8%. CONCLUSION: The disinfectant produced with the established method is simple in preparation, accurate in content determination, stable and reliable in quality.
