Castleman Tumor in Association with Paraneopiastic Pemphigus-A Report of 10 Cases
- VernacularTitle:伴发副肿瘤性天疱疮的Castleman瘤——附10例报告
- Author:
Xuejun ZHU
;
Jing WANG
;
Xixue CHEN
;
Rengui WANG
;
Lanbo ZHANG
;
Ting LI
;
Aiping WANG
;
Shuxia YANG
;
Ping TU
;
Ruoyu LI
;
Yan WU
;
Haizhen YANG
;
Suzhen JI
- Publication Type:Journal Article
- Keywords:
Paraneoplastic Pemphigus;
Giant lymph node hyperplasia
- From:
Chinese Journal of Dermatology
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To obtain a better understaning of the clinical features of Castleman tumor associated paraneoplastic pemphigus. Methods The clinical features and therapy of 10 cases of this disease, diagnosed in the Department of Dermatology of Peking University First Hospital were analyzed. Results Castleman tumor was shown to be the most common neoplasm associated with paraneoplastic pemphigus in China. The clinical presentations, histopathologic characteristics, CT scan findings, and immunologic features were all unique. The early diagnosis and removal of the Castleman tumor are crucial for the treatment of this tumor-associated autoimmune disease. Conclusions Because Castleman tumor is directly related to the induction of autoimmunity, early diagnosis and prompt removal of the tumor are essential to the management of this disease.
