Content Detemination of Paeoniflorin in Refined Coronary Tablets by HPLC
- VernacularTitle:高效液相色谱法测定精制冠心片中芍药苷的含量
- Author:
Chao MENG
;
Shaohua FENG
;
Jing ZHANG
- Publication Type:Journal Article
- Keywords:
HPLC;
Refined coronary tablets;
Paeoniflorin;
Content
- From:
China Pharmacy
2005;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a HPLC method for content determination of paeoniflorin in refined coronary tablets.METHODS:HPLC was performed on Kromasil C18 column at room temperature,the mobile phase consisted of acetonitrile-0.2%phosphoric acid solution(13∶87),the detection wavelength was 230nm with flow rate 1ml/min and sample size 10?l.RESULTS:Paeoniflorin was linear with the peak area in the range of 0.317?g~1.587?g(r=0.9 999),the average recovery was 100.1%(RSD=1.46%).CONCLUSION:The established method is simple,reliable,reproducible and can be used for the quality control of refined coronary tablets.