Effects of berberine on the proliferation of human pulmonary carcinoma cells
- VernacularTitle:小檗碱对人高转移肺癌系(PG)细胞增殖的影响及机制研究
- Author:
Yan JIANG
;
Yi WANG
;
Yu HAO
;
Xuefeng WANG
;
Quanying QIU
;
Qifu HUANG
;
Hui MA
- Publication Type:Journal Article
- Keywords:
Berberine;
PG cell;
Proliferation
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of berberine on the proliferation of human pulmonary carcinoma cells (PG cells). METHODS: The proliferation of PG cells was determined by using MTT assay. Cell cycle and apoptosis of PG cells were determined by using flow cytometry. Confocal scanning imaging system was used to assay the ROS-releasing level of PG cells. RESULTS: Berberine was shown to inhibit proliferation of PG cells directly and in a concentration-dependent manner (P