Effects of loading trehalose into cytoplasm before freeze-drying on platelets activation and response to agonists in vitro
- VernacularTitle:冻干前负载海藻糖对血小板体外激活和聚集反应的影响
- Author:
Faqiang LU
;
Jinghan LIU
;
Xilin OUYANG
- Publication Type:Journal Article
- Keywords:
Trehalose;
Platelets activation;
Aggregation;
Activation inhibitors
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
0.01).After incubation with trehalose for 4h,the expression of CD62p increased,and it decreased when platelets activation inhibitor PGE-1 and adenosine were added to the incubation buffer.The expression of PAC-1 showed no difference among the three groups. Conclusion The preprocessing before platelets lyophilization has no significant effects on the function and activity of platelets when the platelets activation inhibitor is added.
