Do Different Arterial Stiffness Parameters Provide Similar Information in High-Risk Patients for Coronary Artery Disease?.
10.4070/kcj.2013.43.12.819
- Author:
Kyung Min KIM
1
;
Byung Su YOO
;
Anna KO
;
Jeong Min KIM
;
Hyun Sik KIM
;
Jun Won LEE
;
Jang Young KIM
;
Young Jin YOUN
;
Sung Gyun AHN
;
Seung Hwan LEE
;
Junghan YOON
Author Information
1. Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. yubs@yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Pulse wave velocity;
Coronary artery disease;
Arterial stiffness
- MeSH:
Aged;
Arteries;
Constriction, Pathologic;
Coronary Angiography;
Coronary Artery Disease*;
Coronary Vessels*;
Humans;
Male;
Prevalence;
Pulse Wave Analysis;
Vascular Stiffness*
- From:Korean Circulation Journal
2013;43(12):819-824
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The aim of our study was to compare the values of brachial-ankle pulse wave velocity (baPWV) measured with two different non-invasive methods as predictors of coronary artery disease (CAD) in patients who had undergone coronary angiography. SUBJECTS AND METHODS: From 6373 patients who visited our laboratory for non-invasive procedures, we enrolled 965 consecutive patients undergoing coronary angiography. Data for baPWV and peripheral augmentation index (pAI) were recorded. CAD was defined as greater than 50% stenosis of a major epicardial artery in a coronary angiogram. In addition, the severity of CAD was classified as: none/minimal or 1-, 2-, or 3-vessel disease, based on previous or current angiographic findings. RESULTS: Among 965 subjects, the mean age was 63.7+/-11.6 years, and 58.2% were male. Compared with subjects without CAD disease, those with CAD showed higher values of baPWV (16.6+/-3.5 m/sec vs. 15.9+/-3.4 m/sec, p<0.001), and lower values of pAI (73.5+/-15.9% vs. 76.0+/-15.7%, p=0.01). When the severity of CAD was expressed as none/minimal or 1-, 2-, or 3-vessel disease, there was a significant association between the extent of CAD and baPWV (p<0.001). In univariate analysis, high PWV and low pAI were associated with an increased prevalence of CAD (p<0.001). CONCLUSION: Increased baPWV and decreased pAI were associated with the presence of CAD in the elderly.
