Expression of ?-Catenin and LEF-1 in Malignant Melanoma
- VernacularTitle:?联蛋白和淋巴样增强因子1在恶性黑素瘤中的表达
- Author:
Hehui YIN
;
Wenjun LIAO
;
Ying GAO
;
Tianwen GAO
- Publication Type:Journal Article
- Keywords:
Melanoma;
?-catenin;
Lymphoid enhancing factor
- From:
Chinese Journal of Dermatology
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate ?-catenin and lymphoid enhancing factor 1 (LEF-1) expression in malignant melanoma. Methods ?-catenin and LEF-1 protein expression was examined using the PowerVisionTM immunohistochemical method in 25 cases of intradermal nevus and 45 cases of malignant melanoma. Results Comparing malignant melanoma with intradermal nevi, there was a significant difference in the expression of ?-catenin (33/45= 73% vs. 9/25 = 36%, respectively; P
