Study on the Relation of Glycyrrhizic Glycoside on Hepatitis B Virus Replication in Vitro
- VernacularTitle:甘草酸苷与乙型肝炎病毒复制关系的体外研究
- Author:
Xiaohong LIN
;
Hongli XI
;
Xiaoyuan XU
;
Xixian FU
- Publication Type:Journal Article
- Keywords:
Stronger Neo-Minophagen C(SNMC);
Glycyrrhizic glycoside;
Hepatitis B virus;
2.2.15cell
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the relation of glycyrrhizic glycoside on hepatitis B virus(HBV)replication in vitro.METHODS:2.2.15cell line was used and treated with glycyrrhizic glycoside,the contents of HBsAg and HBeAg in the su?pernatant of cell culture with different concentrations of glycyrrhizic glycoside were quantified.RESULTS:The inhibitory rates of glycyrrhizic glycoside on HBsAg were83.8%,71.0%,62.1%,52.0%and29.7%respectively at the concentrations of800,400,200,100and50?g/ml respectively.CONCLUSION:Glycyrrhizic glycoside does not promote HBV replication in vitro experiment.
