Preparation and Quality Control of Compound Dexamethasone Liniment
- VernacularTitle:复方地塞米松搽剂的制备及质量控制
- Author:
Guangjun LIU
;
Huiying WU
;
Chunmei WENG
- Publication Type:Journal Article
- Keywords:
Compound dexamethasone liniment;
Preparation;
Quality control;
HPLC
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for preparation and quality control of compound dexamethasone liniment.METHODS:The compound dexamethasone liniment were prepared with dexamethasone acetate and vitamin E,the contents were determined by HPLC.RESULTS:The calibration curves of dexamethasone acetate and vitamin E were linear in the range of2～40?g/ml and80～800?g/ml respectively,and their average recoveries were100.5%(RSD=0.82%)and98.6%(RSD=0.59%)respectively.CONCLUSION:The preparation is reasonable in formula,simple and accurate in quality control.
