Content Determination of Cyproheptadine Hydrochloride in Fuyan Cream by Simultaneous Equations
- VernacularTitle:联立方程组测定肤炎霜中盐酸赛庚啶的含量
- Author:
Yuanjun CHEN
;
Jinsheng ZHOU
;
Yulan LU
;
Chuang DING
;
Jinlong LIAN
- Publication Type:Journal Article
- Keywords:
Ultraviolet spectrophotometry;
Fuyan cream;
Cyproheptadine hydrochloride;
Simultaneous equations;
Content
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for content determination of cyproheptadine hydrochloride in fuyan cream.METHODS:Ultraviolet spectophotometry was applied to determine the contents of cyprohepatadine hydrochloride as well as its adjuvant as two coexisting components without isolation and extraction,the wavelengths were286nm and258nm res_ pectively,linear regression and simultaneous equations were used to analyze the results.RESULTS:Cyproheptadine hydrochlor_ ide and its adjuvant showed good linear relationship in the range of2.52～25.2and2.5022～25.022?g/ml respectively,the average recovery of cyproheptadine hydrochloride was98.61%(RSD=1.08%).CONCLUSION:The present method is simple,convenient,reproducible and reliable,which is suitable for rapid determination for fuyan cream.
