The morphological and histopathological features of colorectal small flat adenoma
- VernacularTitle:大肠小扁平腺瘤的形态及病理组织学特征研究
- Author:
Shuian TONG
;
Xiyuan HUANG
;
Zihua ZHV
;
Weixiang CHEN
;
Shaohua FEI
;
Jun DING
;
Lingfang YANG
;
Longzhen YE
;
Liujun GU
;
Yunshi SHA
;
Hongfu SUN
- Publication Type:Journal Article
- Keywords:
Colorectal small flat adenoma;
Protein p53;
Oncogene protein p21;
Estrogen receptor;
Progesterone receptor
- From:
Chinese Journal of Digestive Endoscopy
1996;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To be investigated the morphology of colorectal small flat adenoma and the expressions of p53 , p21, ER and PR. Methods Colonoscopy ( Olympus CF 240) and microscopy ( Olympus BV 41) were used to observe 50 cases of colorectal small flat adenomas. The expressions of p53 , p21 , ER, and PR were detected by the two steps of immunohistochemistry in 50 cases of small flat adenomas and the surrounding mucosa, 26 cases of colorectal carcinomas, while 15 cases of the normal colorectal mucosa as control group. Results These lesions were distributed throughout the large bowel, the prevalence in order was transverse colon, sigmoid and rectum. The small flat adenoma was round, flat, or sessile in shape, and sized
