Effects of Single Low-dose Intravenous Injection of Milrinone on Plasma Cardiac Troponin I in Rabbits with Stunned Myocardium
- VernacularTitle:小剂量单次静脉注射米力农对兔顿抑心肌血清cTnI的影响
- Author:
Zixing YAN
;
Jie MA
- Publication Type:Journal Article
- Keywords:
Low-dosage;
Milrinone;
Stunned myocardium;
Cardiac troponin I
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of single low-dose intravenous injection of milrinone on plasma cardiac troponin I(cTnI) in rabbits with stunned myocardium.Methods Thirty rabbits with stunned myocardium were included in this study and they were randomly divided into three groups(10 rabbits a group).In sham-operated group(group A),the left anterior descending branch(LAD) of rabbits were not occluded.In ischemia and stunned myocardium group(group B),the LAD of rabbits were occluded for 15min and perfused for 60min.In milrinone group(group C),the LAD of rabbits were occluded for 15min,injected with low-dosage(5ug/kg) of milrinone,and perfused for 60min.Results The content of plasma cTnI in group C was decreased significantly than that in group B(P
