The Effects of Repeated Thermotherapy on the Apoptosis of HepG2 Cells
- VernacularTitle:重复加热对肝癌HepG2细胞凋亡的影响
- Author:
Chunhong QIN
;
Yongguo LI
;
Lunxiang ZHOU
- Publication Type:Journal Article
- Keywords:
Thermotherapy;
HepG2 cell;
Apoptosis;
Bcl-2;
Bax
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the apoptosis rate and the mRNA and protein expressions of Bcl-2 and Bax in the remained HepG2 cells after successive thermotherapy for 10 days.Methods After the HepG2 cells were treated with ten repeated cycles of heat exposure at 43℃ for 80 minutes twice a day,the rate of apoptosis was analyzed,and the mRNA and protein expressions of Bcl-2 and Bax were detected.Results Before and after treatment with heat,the apoptosis rates of HepG2 cells were(9.0%?0.8%) and(5.8%?1.3%) respectively(P