A Study of the Safety and Efficacy of Children's Skin Products.
- Author:
Ji Hwan HWANG
;
Tae Eun KWON
;
Jong Seong AHN
;
Young Gull KIM
;
Kyu Han KIM
;
Kyoung Chan PARK
- Publication Type:Original Article
- Keywords:
Atopic dermatitis;
Children's skin products;
CD44;
Seborrheic keratosis;
Basal cell carcinoma;
Squamous cell carcinoma
- MeSH:
Allergens;
Carcinoma, Basal Cell;
Carcinoma, Squamous Cell;
Child;
Dermatitis;
Dermatitis, Atopic;
Erythema;
Humans;
Hydrogen-Ion Concentration;
Infant;
Irritants;
Keratinocytes;
Keratosis, Seborrheic;
Skin*;
Soaps;
Volunteers
- From:Korean Journal of Dermatology
1999;37(4):468-474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Atopic dermatitis, characterized by dry, flasky, easily irritated skin, is the most common form of dermatitis seen during childhood. Infants with atopic dermatitis and other eczematous conditions need special dermatologic care to hydrate their skin and to minimize contact with irritants or allergens. OBJECTIVE: The purpose of our study is to evaluate the safety and efficacy of the skin products developed for children. METHODS: Twenty-eight normal children and 26 children with atopic dermatitis were evaluated clinically after using following commercal skin products : (lotion, cream, shampoo, soap, face wash wash) for 2 weeks. Water content of the skin of 14 volunteers was measured serialy over 8 haurs at 2 hour intervals after the application of each skin product. The skin pH of 16 volunteers was also measured serialy over 60 minutes at 30 minute intervals after application. We performed visual skin erythema grading, skin erythema grading by dermaspectrometer, transepidermal water loss measurement, skin water content measurement, and keratinocyte morphology observation by D-squame after the application of the skin products to 13 volunteers for 4 days.
