Effects of venous thrombosis on endothelial cells in remote non-thrombosed vein
- VernacularTitle:静脉血栓形成对大鼠非血栓段静脉血管内皮细胞的影响
- Author:
Feng GAO
;
Xiaoqiang LI
- Publication Type:Journal Article
- Keywords:
Venous thrombosis;
Inflammation;
Endothelial cell;
Apoptosis
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the functional changes of endothelial cells (EC) in non-thrombosis vein segment (ECNT) in rats with experimental venous thrombosis (VT). MethodRats were divided into normal, control, and thrombosis group caused by legating a portion of iliac vein with 30 animals in each group. Endothelium was sampled from superhepatic IVC. Samples were studied by electroscopy, immunohistochemistry, and Western blotting for apoptosis. ResultsMorphological and functional changes of the ECs were observed in sampled superhepatic IVC. Compared with normal and control group the apoptosis rates(P
