A Case of Leukocytoclastic Vasculitis Associated with Antiphospholipid Antibody Syndorme.
- Author:
Tae Hyun KIM
;
Eung Ho CHOI
;
Sang Min HWANG
;
Sung Ku AHN
- Publication Type:Case Report
- Keywords:
Antiphospholipid antibody syndrome;
Leukocytoclastic vasculitis;
Deep vein thrombosis
- MeSH:
Antibodies, Antiphospholipid*;
Antiphospholipid Syndrome;
Arteries;
Giant Cell Arteritis;
Humans;
Livedo Reticularis;
Male;
Polyarteritis Nodosa;
Skin;
Thrombosis;
Vasculitis*;
Vasculitis, Leukocytoclastic, Cutaneous;
Veins;
Venous Thrombosis
- From:Korean Journal of Dermatology
1999;37(4):519-522
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The antiphospholipid antibody syndrome is an acquired multisystemic disorder characterized by persistent elevated antiphospholipid antibodies and/or hypercoagulation in veins or arteries, or both. The clinical manifestations of the antiphospholipid antibody syodrome are recurrent thrombosis, fetal loss, thrcenbocytopenia, and various cutaneous lesions. Skin lesions are the first sign of this syndrome in 41% of patients and systemic thrombosis develops in 40% of them. Livedo reticularis is the most common cutaneous finding of the antiphosphotipid antibody syndrome. Although vasculitis has not been frequently noted in antiphospholipid antibody syndrome, some vasculitis such as polyarteritis nodosa, giant cell arteritis, and other nonspecific vasculitides have been found in association with antiphospholipid antibody syndrome. We present a male patient with typical manifestations of leukocytoclastic vasculitis with deep vein thrombosis and positive antiphospholipid antibodies. It suggests that a case of antiphospholipid antibody syndorme was accompanied with cutaneous leukocytoclastic vasculitis.
