Measures of cell turnover (apoptosis and proliferation) and their association with survival in gastric cancer
- VernacularTitle:胃癌细胞凋亡与增殖的细胞转换与生存的关系
- Author:
Jinming CHEN
;
Haibo ZHOU
;
Liang ZHANG
;
Weihua LI
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Apoptosis;
Cell proliferation;
Survival;
Flow cytometry
- From:
Chinese Journal of Pathophysiology
1999;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the ratio of apoptotic index and proliferative index (AI/PI) in gastric cancer and their association with survival. METHODS: The apoptotic population and the proliferative population were quantitatively analyzed by flow cytometry. The proliferative cells were identified by confocal microscope and Kaplan-Meier method was used to analyze survival. RESULTS: AI and PI were strongly correlated with a Pearson coefficient of 0.58 (P
