Overexpression of CLN3 gene in human ovarian carcinoma
- VernacularTitle:CLN3基因在卵巢癌中过表达的研究
- Author:
Dongwei MAO
;
Yiping ZHAO
;
Keshen LI
;
Xiaoming WANG
- Publication Type:Journal Article
- Keywords:
Ovarian neoplasms;
Genes, CLN3;
Gene expression
- From:
Chinese Journal of Pathophysiology
1999;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To determine whether overexpression of CLN3 is involved in the tumorigenesis of ovarian cacinoma. METHODS: 10 specimens of ovarian carcinoma were screened for CLN3 gene expression level by semiquantitative RT-PCR and Western blotting. RESULTS: Overexpression of CLN3 mRNA and protein was found in all ovarian tumor tissues as compared with normal tissues. CONCLUSION: The overexpression of CLN3 may contribute to tumor development of ovarian cancer.
