Study on the Compatible Stability of Doxofylline Injection and Dexmethasone Sodium Phosphate Injection
- VernacularTitle:多索茶碱注射液与地塞米松磷酸钠注射液配伍稳定性考察
- Author:
Xiangqian PENG
- Publication Type:Journal Article
- Keywords:
Doxofylline injection;
Dexmethasone sodium phosphate injection;
Compatibility;
Stability;
HPLC
- From:
China Pharmacy
2005;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatible stability of doxofylline injection and dexmethasone sodium phosphate injection.METHODS:The changes in appearance and pH value of the mixture of doxofylline injection and dexmethasone sodium phosphate injection in 5%glucose injection within 6 hours at 25℃were observed and determined,the content of which was determined by HPLC.RESULTS:Compared with the solution at 0h of mixing,no significant changes were noted in color,clarity and content within 6 hours' mixing,however,there was an increase in its pH value.CONCLUSION:The mixture of doxophylline and dexmethasone in 5%glucose injection is stable in quality within 6 hours' mixing at 25℃.
