Relation of serum leptin to birth weight and insulin in preterm and term neonates
- VernacularTitle:早产和足月新生儿血清瘦素与出生体重及胰岛素关系分析
- Author:
Xinli WANG
;
Yunpu CUI
;
Hongmao YE
- Publication Type:Journal Article
- Keywords:
Leptin;
Insulin;
Birth weight;
Infant, premature;
Infant, newborn
- From:
Chinese Journal of Perinatal Medicine
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigation the relation of leptin to birth weight and insulin in preterm and term neonates and to explore whether a functional “adipoinsular axis” might exist in preterm and term neonates. Methods A total of 264 preterm and term newborns were recruited and categorised according to gestation length. Anthropometric measurements were performed at birth. Leptin, fasting glucose and insulin were measured at 3 days of life. Results Serum leptin was significantly higher in term than in preterm. The relation between serum leptin and gestation followed a non-linear pattern; The slope of the curve began to increase after 34 weeks gestation. Serum leptin was associated with birth weight and insulin in newborn more than 32 weeks gestation(r=0.240, 0.227, P
