Expression of C-MET in thyroid carcinoma with cervical lymph node metastases and its clinical significance
- VernacularTitle:C-MET蛋白在有颈部淋巴结转移的甲状腺癌中的表达和意义
- Author:
Chunxu ZHANG
;
Qiang WANG
;
Youlei ZHANG
- Publication Type:Journal Article
- Keywords:
Thyroid Neoplasms/pathol;
Lymph Node Metasis;
C-MET Protein
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of C-MET in papillary thyroid carcinoma(PTC) with (cervical) lymph node metastases, PTC without cervical lymph node metastases,follicular thyroid carcinoma and benign thyroid disease and the clinical significance. Methods The expression level of C-MET was examined by immunohistochemical analysis with C-MET monoclonal antibody in 62 cases of PTC with cervical lymph node metastases, 50 cases of PTC without cervical lymph node mestastases, 10 cases of follicular (thyroid) (carcinoma) and 30 cases of benign thyroid disease. Results PTC with cervical lymph node metastases (expressed) significantly greater level of C-MET than the other forms of thyroid carcinoma and benign thyroid disease(P
