DNA Sequencing of HPV cp6108 Gene
- VernacularTitle:人乳头瘤病毒cp6108的序列研究
- Author:
Mingjun JIANG
;
Shuqi WANG
;
Yanhua YU
;
Yueping YIN
;
Guozhu HAN
;
Jianfang SUN
- Publication Type:Journal Article
- Keywords:
Papillomavirus, human;
HPV cp6108;
Sequence analysis;
DNA
- From:
Chinese Journal of Dermatology
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study LI gene sequence of HPV cp6108 from 5 cases of condyloma acuminata. Methods T-A cloning and direct sequencing of PCR product were used. Results The LI gene sequences of HPV cp6108 from 5 specimens were presented with the homology of 99% to reference sequence in GenBank. A total of 3 gene mutations were found, including a nonsense mutation of G70A, a missense mutation of D77N, and a missense mutation of Tl16P. Conclusions In comparison with the sequence in GenBank, at least 3 gene mutations of HPV CP6108, i.e. one nonsense mutation of G70A and missense mutations of D77N and Tl 16P, are found in the present study.
