The Effect of Hydroxypropyl-?-Cyclodextrin on the Stability of Potassium Dehydroandrographolide Succinate Solution
- VernacularTitle:羟丙基-?-环糊精对穿琥宁溶液稳定性的影响
- Author:
Ting ZHANG
;
Pingsheng XU
;
Xinzhong LI
- Publication Type:Journal Article
- Keywords:
HP-?-CD;
Potassium dehydroandrographolide succinate;
Stability
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effect of HP-?-CD on the stability of potassium dehydroandrographolide succina_ te solution.METHODS:The stability of the testing group(potassium dehydroandrographolide succinate solution+HP-?-CD)was determined by a thermostatic accelerated test with the content variation of potassium dehydroandrographolide succi?nate solution as an index and the potassium dehydroandrographolide succinate solution that was free of HP-?-CD as the control.RESULTS:The content variation of the testing group was less as against the control group,the terms of validity for the2groups were0.657y and3.40y respectively.CONCLUSION:The stability of potassium dehydroandrographolide succi?nate solution can be increased by adding HP-?-CD to which.
