Study on the Compatible Stability of Foscarnet Sodium Injection with 4 Infusion Solutions
- VernacularTitle:膦甲酸钠注射液与4种大输液的配伍稳定性考察
- Author:
Hongxia HU
- Publication Type:Journal Article
- Keywords:
Foscarnet sodium injection;
Infusion solutions;
Compatibility;
UV-spectrophotometry;
Stability
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatible stability of foscarnet sodium injection with5%glucose injection,10% glucose injection,glucose saline and NaCl injection.METHODS:The content changes of foscarnet sodium injection were determined by UV-spectrophotometry at different time within8h after mixing with 4 kinds of infusion solutions,the appearance description of the solution was observed,the pH value and the UV scan spectra changes of foscarnet sodium were determined.RESULTS:No marked changes were noted in the contents,appearance,pH value and the UV-scan spectra of the mixed solutions.CONCLUSION:Foscarnet sodium injection can be used with in 8h after mixing with 4 infusion solutions under the room temperature.