Murine CD200~+CK7~+ trophoblasts in poly (I∶C)-induced embryo resorption model
- VernacularTitle:多聚次黄苷酸-胞苷酸诱发性小鼠流产模型CD200~+CK7~+滋养层细胞分析
- Author:
Yi LIN
;
Yaoying ZENG
;
Jingfang DI
;
Shan ZENG
;
Jingxian ZHAO
;
Tong WANG
;
Xiangfeng ZENG
;
Zheng FENG
- Publication Type:Journal Article
- Keywords:
Abortion;
Trophoblast;
Keratin
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the relationship between CD200~+CK7~+ trophoblasts and the resorption of embryos in a poly (I∶C)-induced abortion model. METHODS: The status of CD200 expression was investigated in Balb/c?C57BL/6 and Balb/c?Balb/c mice as induced model of embryo-resorption by an i.p. injection of poly (I∶C). CD200 expression on CK7~+ cells from placentas was detected with flow cytometry. CD200~+ cells in placenta were observed with immunocytochemical staining. RESULTS: Both the percentage and absolute number of CD200~+CK7~+ cells were dramatically decreased by injection of poly (I∶C) in Balb/c?C57BL/6 (6.3%?6.2% vs 36.1%?9.3%, P
