The coordinated regulation between nuclear DNA and mitochondria DNA
- VernacularTitle:细胞核基因组与线粒体基因组的相互调控
- Author:
Lifeng CHEN
;
Junze LIU
- Publication Type:Journal Article
- Keywords:
DNA, mitochondrial;
DNA, nuclear;
Genes
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The overall cellular gene expression is well realized by the coordinated regulation between nuclear DNA and mitochondria DNA. Coordinated regulation between two genomes plays a key role not only in mitochondria biogenesis and protein synthesis but also more importantly in the regulation of gene expression of mitochondria respiratory chain subunits in order to mediate the mitochondrial respiratory function. In the present review, we focus on the mechanism of coordinated regulation between two genomes.
