Magnifying endoscopic manifestation of gastric atrophy, intestinal metaplasia or dysplasia and its diagnostic value
- VernacularTitle:胃黏膜萎缩、肠上皮化生及异型增生的放大内镜表现及其诊断价值
- Author:
Yonghui HUANG
;
Liya ZHOU
;
Sanren LIN
;
Zhu JIN
;
Jianjun LIU
;
Shigang DING
;
Zhiwei XIA
;
Liping DUAN
;
Hong CHANG
- Publication Type:Journal Article
- Keywords:
Magnifying endoscopy;
Gastric mucosa;
Atrophy;
Intestinal metaplasia;
Dys plasia
- From:
Chinese Journal of Digestive Endoscopy
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study on the results of magnifying endoscopy in gastric atrophy, intestinal metaplasia (IM) and dysplasia, and evaluate their feasibility and accuracy for the diagnosis of these lesions. Methods One hundred patients were examined by magnifying endoscopy, Fujinon EG485 ZH modal, and stained with 0. 5% methylene blue. After defining magnifying endoscopic patterns of gastric pits as types A, B, C, D, and E, the diagnostic classification and endoscopic criteria were developed for the diagnosis of atrophy, IM and dysplasia. The results of 417 histopathological biopsy specimens taken from the corresponding areas of gastric mucosa under magnifying endoscopy were regarded as gold standard. Results Sparse and thick gastric pits mainly appeared in gastric atrophy, IM mainly appeared in gastric mucosa of type C, type D, and type E with positive stain, dysplasia appeared as depressed, slightly raised, or flat mucosa accompanied by loss of clear pattern, fine pits or coarse and irregular microstructure. The sensitivity and specificity of magnifying endoscopies in the diagnosis of atrophy, IM and dysphasia were 95. 85% , 95. 09% ; 88. 30% , 90.83% ; and 91.52% , 94. 41% respectively, all were higher than those of routine endoscopy. Conclusion The diagnostic accuracy significantly increased as depending upon the morphological features of gastric atrophy , IM, or dysplasia under magnifying endoscopy.
