Evaluation of topical pharyngeal anesthesia in gastroscopy and factors related to the tolerance of patient: a randomized double-blind placebo-controlled study
- VernacularTitle:胃镜检查中咽部表面麻醉及患者耐受性的相关因素分析
- Author:
Qi ZHU
;
Qi WU
;
Jie ZHONG
;
Jihong TAN
;
Shihu JIANG
;
Qingbo HE
- Publication Type:Journal Article
- Keywords:
Gastroscopy;
Anesthesia, local;
Regression analysis
- From:
Chinese Journal of Digestive Endoscopy
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study on the efficiency of topical pharyngeal anesthesia in gastroscopy and the factors related to the tolerance of patients. Methods A randomized double-blind placebo-controlled study was conducted. Two hundred and three subjects consented to participate in this study underwent gastroscopy. Relative Risks (RR) of patients' discomfort in pharyngeal anesthesia were calculated, anxiety and other potential confounding factors by using logistic regression analysis. Results Compared with placebo controls, the RR of patient discomfort on intubation was 0.37 (95 % CI 0. 20-0. 70) , patients aged less than 40 years had RR higher than those of aged 40 or over ( RR 2. 13 , 95% CI 1. 09-4. 15 ) . With subgroup analysis in those patients less than 40 years old and undergoing gastroscopy for the first time, the RR of patients' discomfort was 0. 23 (95% CI 0. 07-0. 77) and 0. 24 (95% CI 0. 10-0. 58) for the topical anesthesia. Conclusion Topical pharyngeal anesthesia appears to be effective in diminishing the discomfort during endoscopy in patients less than 40 years old and those undergoing the procedure first time. Trait-anxiety is not a predictor of discomfort.
