The effect of Shenfu injection on ischemia reperfusion injury of rat liver graft
- VernacularTitle:参附注射液对大鼠移植肝脏缺血再灌注损伤的影响
- Author:
Weihua ZHU
;
Xisheng LENG
;
Jiye ZHU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Reperfusion injury;
Shenfu injection
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Shenfu injection on ischemia reperfusion injury of rat liver graft. Methods Male SD rats were used as isogeneic orthotopic liver transplantation. Sixty rats were randomly divided into two groups(30 in each). The recipient received Shenfu injection intravenously immediately before the removal of the liver in SF group and normal saline of the same volume in control group. At 3、6 and 24h after the reperfusion blood and hepatic tissue were sampled for examination. Results The levels of superoxide dismutase (SOD) and nitric oxide (NO) in SF group significantly increased compared with those in control group(P
