Analysis of1139Case of Drug-induced Hemorrhage
- VernacularTitle:药源性出血1139例分析
- Author:
Shumin YANG
;
Ming LI
;
Jizhang YANG
- Publication Type:Journal Article
- Keywords:
Adverse drug reaction;
Hemorrhage;
Analysis
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To discuss the general regularity and characteristics of drug-induced hemorrhage.METHEDS:1139cases of drug-induced hemorrhage reported in internal medical journals published from Jan.1995to Dec.2004were collected and analyzed.RESULTS:The drugs that induced hemorrhage were chiefly antimicrobial drugs,central nervous system drugs and hematopoietic system drugs;oral drugs were the chief means that lead to hemorrhage which amounted to63.92%of the total hemorrhage cases;the bleeding parts were mainly alimentary tract and intestinal tract;the bleeding time usually occurred within2min~1mo after medication.Systematic administration-induced hemorrhage usually occurred under the normal administration and dosage;however,wrong use of drugs,irrational drug uses etc.were accountable for the hem?orrhage in local application.CONCLUSION:Clinicians should give detailed guidance to patients on the drug use so as to avoid wrong or irrational drug use.