POEMS syndrome: a case report.
- Author:
Jae Woo KIM
1
;
Sang Kun LEE
;
Kyung Min HA
;
Ki Ho KIM
;
Gwang Yeol JOH
;
Hyo Jin KIM
;
Seoung Oh YANG
;
Sook Hee HONG
Author Information
- Publication Type:Case Reports ; Review
- Keywords: POEMS syndrome; Monoclonal protein; Osteosclerotic myeloma
- MeSH: Adult; Biopsy; Femur Neck/pathology; Humans; Magnetic Resonance Imaging; Male; Multiple Myeloma/complications/pathology; POEMS Syndrome/complications/*diagnosis
- From:Journal of Korean Medical Science 1992;7(1):79-84
- CountryRepublic of Korea
- Language:English
- Abstract: POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
