Study on Extraction of Baicalin from Scutellaria Baicalensis Georgi
- VernacularTitle:黄芩中黄芩苷提取工艺的研究
- Author:
Jihong NIE
;
Ping WANG
- Publication Type:Journal Article
- Keywords:
Baicalin;
Content determination;
Extraction technique;
Single factor test;
Orthogonal test
- From:
China Pharmacy
2005;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for content determination of baicalin in Scutellaria baicalensis Georgi extract and to optimize the extraction technique.METHODS:The content of baicalin was adopted as index and was deter?mined by HPLC;Single factor test and orthogonal test were employed to optimize the extraction technique.RESULTS:The detected concentration of baicalin showed a good linear relation in the range of0.05912~0.02956mg/ml(r=0.99974),the average recovery was99.5%,RSD=1.10%(n=5);The optimal technique was twice recirculation in water solvent14times the amount of Scutellaria baicalensis Georgi flour,each time for1hour.CONCLUSION:The established method is conve?nient,and the extraction technique is stable,reasonable and practicable.