T_1 and T_2 lymphocyte subset alterations in patients with colorectal cancer
- VernacularTitle:大肠癌患者外周血T_1和T_2淋巴细胞变化规律的研究
- Author:
Ming CUI
;
Shan WANG
;
Yingjiang YE
;
Zhirong CUI
;
Yang KE
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
T lymphocytes
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purpose of this study was to analyze the alterations of T_1、T_2 lymphocyte subsets in the peripheral blood of patients with colorectal cancer. MethodsTwenty patients with primary colorectal cancer were enrolled into this study, T_1 and T_2 in the peripheral blood were evaluated by detecting the intracellular interferon-? and interleukin-4 production with 4-color flow cytometry. ResultsThe percentage of T_1 and T_2 in the peripheral blood of cancer patients was lower significantly than healthy controls [(36?11)% and 3.3(1.9)% vs. (46?12)% and 4.1(3.1)%](P